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- Yale Pediatric Endocrinology1 Long Wharf DriveNew Haven, CT 06511
- Yale Diabetes ClinicDana Clinic Building789 Howard Avenue, Ste 2nd FloorNew Haven, CT 06519
- 8 Devine StreetNorth Haven, CT 06473
Ania Jastreboff, MD, PhD
Obesity Medicine, Pediatric Endocrinology & Diabetes, Diabetes Medicine & Management, Endocrinology
Telehealth is available
Patient type treated
Child, Adult
Accepting new patients
Yes
Referral required
From patients or physicians
Board Certified in
Internal Medicine, Pediatrics, Endocrinology Diabetes & Metabolism, Pediatric Endocrinology
, and Obesity Medicine
Biography
Ania M. Jastreboff, MD, PhD, is an adult and pediatric endocrinologist with expertise in obesity medicine and weight management. She cares for patients who have prediabetes, insulin resistance, metabolic syndrome, and type 1 and type 2 diabetes.
Dr. Jastrebroff, who is director of the Yale Obesity Research Center (Y-Weight), says she empathizes with patients who struggle to lose weight or maintain weight loss. “Carrying excess weight and having obesity is not a lifestyle choice. Obesity is a chronic disease and should be treated with the same vigor and integrity as other chronic diseases,” she says. “We are in the infancy of our understanding of the mechanisms that underlie obesity. Many novel treatments are under development, including new anti-obesity medications, endoscopic procedures, and the refining of behavioral and surgical interventions.”
An assistant professor of medicine (endocrinology) and of pediatrics (endocrinology) at Yale School of Medicine, Dr. Jastrebroff says one of her goals is to conduct clinic research that will lead to better treatments for obesity and also have a clear public health impact in mitigating the obesity “pandemic.”
Titles
- Associate Professor of Medicine (Endocrinology)
- Director, Yale Obesity Research Center (Y-Weight)
- Co-Director, Yale Center for Weight Management
Education & Training
- Clinical Research ScholarYale University School of Medicine (2013)
- PhDYale University Graduate School of Arts and Sciences (2011)
- Endocrinology Postdoctoral FellowshipYale University (2011)
- Pediatric Endocrinology Postdoctoral FellowshipYale University (2011)
- Chief ResidentUniversity of Maryland (2006)
- ResidencyUniversity of Maryland School of Medicine (2006)
- MDUniversity of Maryland at Baltimore (2002)
- BABucknell University, Art History (1998)
Additional Information
Honors & Recognitions
- Young Physician-Scientist Award: American Association for Clinical Investigation (ASCI) (2013)
- First Place Poster Award, Yale Multi-Disciplinary Endocrinology & Metabolism Retreat: Yale Univeristy (2013)
- American Diabetes Association Young Investigator Travel Grant Award: American Diabetes Association (ADA) (2013)
- Burroughs Wellcome Fund Travel Award, Translational Science Meeting 2013: Burroughs Wellcome Fund (2013)
- Translational Science Poster Award : Association for Clinical Research Training and Society for Clinical and Translational Science (2013)
- Diabetes Endocrinology Research Center (DRC), Poster Awardee: Yale University (2011)
- Yale Pediatric Fellows’ Research Day, Oral presentation award winner: Yale University (2011)
Board Certifications
- AB of Obesity Medicine, Obesity Medicine (2016)
- AB of Internal Medicine, Endocrinology Diabetes & Metabolism (2012)
Professional Service
- WTNH (Channel 8) (2020): WTNH (Channel 8) On Call: Keto Diet – TV interview on news station: https://www.wtnh.com/news/health/news-8-on-call-keto-diet/
- WTNH (Channel 8) (2020): WTNH (Channel 8). Top 3 dieting trends of 2020. Live TV interview on news station: https://www.wtnh.com/on-air/gmct-at-nine/top-3-dieting-trends-of-2020/
- Better Health (2019): Better Health. 12 diets you should never try, according to health experts. https://www.eatthis.com/unhealthiest-diets-experts/
- Better Health (2019): Better Health. Healthy gifts that are doctor recommended. https://www.eatthis.com/healthy-gifts/
- WTNH (Channel 8) (2019): WTNH (Channel 8) On Call: New policy for children with severe obesity – TV interview on news station: https://www.wtnh.com/lifestyle/health-news/news-8-on-call-new-policy-for-children-with-severe-obesity/
- Huffington Post (2019): Huffington Post. This is your body on Keto. https://www.huffpost.com/entry/keto-effects-body_l_5d9b58abe4b099389803e441
- Health Central (2019): Health Central. When diet and exercise aren’t enough. https://www.healthcentral.com/article/obesity-treatments
- WTNH (Channel 8) (2019): WTNH (Channel 8) Dealing with Diabetes on Campus – Live TV interview on news station: https://www.wtnh.com/on-air/dealing-with-diabetes-on-campus/
- ADA (American Diabetes Association) (2019 - Present): Obesity/Pathogenesis of Obesity Subcommittee
- NIH (2019): NIH Study Section ad hoc reviewer KNOD: Kidney, Nutrition, Obesity, and Diabetes
Publications
- Jastreboff A, Kaplan L, Hartman M. Triple-Hormone-Receptor Agonist Retatrutide for Obesity. Reply. New England Journal Of Medicine 2023, 389: 1629-1630. PMID: 37888927, DOI: 10.1056/nejmc2310645.
- Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trialGrilo C, Lydecker J, Jastreboff A, Pittman B, McKee S. Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial. Obesity 2023, 31: 2762-2773. PMID: 37751990, PMCID: PMC10600891, DOI: 10.1002/oby.23898.
- Kelly A, Arslanian S, Hesse D, Iversen A, Körner A, Schmidt S, Sørrig R, Weghuber D, Jastreboff A. Reducing BMI below the obesity threshold in adolescents treated with once‐weekly subcutaneous semaglutide 2.4 mg. Obesity 2023, 31: 2139-2149. PMID: 37196421, DOI: 10.1002/oby.23808.
- Garvey W, Frias J, Jastreboff A, le Roux C, Sattar N, Aizenberg D, Mao H, Zhang S, Ahmad N, Bunck M, Benabbad I, Zhang X, investigators S, Abalos F, Manghi F, Zaidman C, Vico M, Aizenberg D, Costanzo P, Serra L, MacKinnon I, Hissa M, Vidotti M, Saraiva J, Alves B, Franco D, Moratto O, Murthy S, Goyal G, Yamasaki Y, Sato N, Inoue S, Asakura T, Shestakova M, Khaykina E, Troshina E, Vorokhobina N, Ametov A, Tu S, Yang C, Lee I, Huang C, Ou H, Freeman G, Machineni S, Klein K, Sultan S, Parsa A, Otero-Martinez J, Gonzalez A, Bhargava A, Brian S, Ince C, Plantholt S, Cole J, Lacour A, Vega D, de Souza J, Rohlf J, St. John R, Horowitz B, Audish H, Galindo R, Umpiperrez G, Ard J, Curtis B, Garvey W, Fraser N, Mandry J, Mohseni R, Mayfield R, Powell T, Vance C, Ong S, Lewy-Alterbaum A, Murray A, Al-Karadsheh A, Yacoub T, Roberts K, Fried D, Rosenstock J, Pulla B, Bode B, Frias J, Klaff L, Brazg R, Van J, Tan A, Briskin T, Rhee M, Chaicha-Brom T, Hartley P, Nunez L, Cortes-Maisonet G, Soucie G, Hsia S, Jones T. Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial. The Lancet 2023, 402: 613-626. PMID: 37385275, DOI: 10.1016/s0140-6736(23)01200-x.
- Rosenstock J, Frias J, Jastreboff A, Du Y, Lou J, Gurbuz S, Thomas M, Hartman M, Haupt A, Milicevic Z, Coskun T. Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA. The Lancet 2023, 402: 529-544. PMID: 37385280, DOI: 10.1016/s0140-6736(23)01053-x.
- Jastreboff A, Kaplan L, Frías J, Wu Q, Du Y, Gurbuz S, Coskun T, Haupt A, Milicevic Z, Hartman M. Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial. New England Journal Of Medicine 2023, 389: 514-526. PMID: 37366315, DOI: 10.1056/nejmoa2301972.
- Bautista T, Fogelman N, Lartigue S, Silverman W, Jastreboff A, Sinha R. Association between specific types of parent stressors and fast-food consumption among parents and children. Eating Behaviors 2023, 49: 101724. PMID: 37054487, PMCID: PMC10247538, DOI: 10.1016/j.eatbeh.2023.101724.
- Weghuber D, Khandpur N, Boyland E, Mazur A, Frelut M, Forslund A, Vlachopapadopoulou E, Erhardt É, Vania A, Molnar D, Ring‐Dimitriou S, Caroli M, Mooney V, Forhan M, Ramos‐Salas X, Pulungan A, Holms J, O'Malley G, Baker J, Jastreboff A, Baur L, Thivel D. Championing the use of people‐first language in childhood overweight and obesity to address weight bias and stigma: A joint statement from the European‐Childhood‐Obesity‐Group (ECOG), the European‐Coalition‐for‐People‐Living‐with‐Obesity (ECPO), the International‐Paediatric‐Association (IPA), Obesity‐Canada, the European‐Association‐for‐the‐Study‐of‐Obesity Childhood‐Obesity‐Task‐Force (EASO‐COTF), Obesity Action Coalition (OAC), The Obesity Society (TOS) and the World‐Obesity‐Federation (WOF). Pediatric Obesity 2023, 18: e13024. PMID: 37002830, DOI: 10.1111/ijpo.13024.
- Aronne L, Jastreboff A, Le Roux C, Malik R, Ahmad N, Liu B, Bunck M, Zhang S, Stefanski A, Lautenbach A. Tirzepatide reduces body weight across body mass index (BMI) categories: A SURMOUNT-1 pre-specified analysis. Diabetologie Und Stoffwechsel 2023, 18: s42-s43. DOI: 10.1055/s-0043-1767938.
- New Frontiers in Obesity Treatment: GLP-1 and Nascent Nutrient-Stimulated Hormone-Based TherapeuticsJastreboff A, Kushner R. New Frontiers in Obesity Treatment: GLP-1 and Nascent Nutrient-Stimulated Hormone-Based Therapeutics. Annual Review Of Medicine 2023, 74: 125-139. PMID: 36706749, DOI: 10.1146/annurev-med-043021-014919.
- Aronne L, Bramblette S, Ingelfinger J, Jastreboff A, Machineni S, Massie N, Rosen C. When Weight Impacts Health. New England Journal Of Medicine 2023, 388: e2. PMID: 36630621, DOI: 10.1056/nejmp2215794.
- Kahn S, Anderson C, Buse J, Selvin E, Angell S, Aroda V, Castle J, Cheng A, Danne T, Echouffo-Tcheugui J, Florez J, Gadgil M, Gastaldelli A, Green J, Jastreboff A, Kanaya A, Kandula N, Kovesdy C, Laiteerapong N, Nadeau K, Pop-Busui R, Powe C, Rebholz C, Rickels M, Sattar N, Shaw J, Sims E, Utzschneider K, Vella A, Zhang C. "The Times They Are A-Changin'" at Diabetes Care. Diabetes Care 2022, 46: 3-5. PMID: 36548704, DOI: 10.2337/dci22-0045.
- Aronne L, Bramblette S, Huett-Garcia A, Ingelfinger J, Jastreboff A, Machineni S, Massie N, Rosen C. Weight and Health — Pathophysiology and Therapies. New England Journal Of Medicine 2022, 387: e62. PMID: 36516089, DOI: 10.1056/nejmp2214423.
- Chouairi F, Mullan C, Ahmed A, Bhinder J, Guha A, Miller P, Jastreboff A, Fuery M, Chiravuri M, Geirsson A, Desai N, Maulion C, Sen S, Ahmad T, Anwer M. Clinical implications of Type 2 diabetes on outcomes after cardiac transplantation. PLOS ONE 2022, 17: e0273111. PMID: 36516178, PMCID: PMC9750001, DOI: 10.1371/journal.pone.0273111.
- Bini J, Gallezot J, Li S, Lim K, Emery P, Kapinos M, Ropchan J, Nabulsi N, Jastreboff A, Huang Y, Carson R. RF12 | PSUN106 Quantifying Liver and Brain Levels of 11β-hydroxysteroid Dehydrogenase Type 1 in Obesity Using Positron Emission Tomography Imaging. Journal Of The Endocrine Society 2022, 6: a29-a30. PMCID: PMC9624872, DOI: 10.1210/jendso/bvac150.062.
- Friedman AN, Schauer PR, Beddhu S, Kramer H, le Roux C, Purnell JQ, Sunwold D, Tuttle KR, Jastreboff AM, Kaplan LM. Obstacles and opportunities in managing coexisting obesity and CKD: Report of a scientific workshop cosponsored by the National Kidney Foundation and The Obesity Society. Obesity 2022, 30: 2340-2350. PMID: 36268562, DOI: 10.1002/oby.23599.
- Friedman AN, Schauer PR, Beddhu S, Kramer H, le Roux CW, Purnell JQ, Sunwold D, Tuttle KR, Jastreboff AM, Kaplan LM. Obstacles and Opportunities in Managing Coexisting Obesity and CKD: Report of a Scientific Workshop Cosponsored by the National Kidney Foundation and The Obesity Society. American Journal Of Kidney Diseases 2022, 80: 783-793. PMID: 36280397, DOI: 10.1053/j.ajkd.2022.06.007.
- Jastreboff AM, Aronne LJ, Stefanski A. Tirzepatide Once Weekly for the Treatment of Obesity. Reply. New England Journal Of Medicine 2022, 387: 1434-1435. PMID: 36239655, DOI: 10.1056/nejmc2211120.
- Bini J, Parikh L, Lacadie C, Hwang JJ, Shah S, Rosenberg SB, Seo D, Lam K, Hamza M, De Aguiar RB, Constable T, Sherwin RS, Sinha R, Jastreboff AM. Stress-level glucocorticoids increase fasting hunger and decrease cerebral blood flow in regions regulating eating. NeuroImage Clinical 2022, 36: 103202. PMID: 36126514, PMCID: PMC9486604, DOI: 10.1016/j.nicl.2022.103202.
- Fogelman N, Schwartz J, Chaplin TM, Jastreboff AM, Silverman WK, Sinha R. Parent Stress and Trauma, Autonomic Responses, and Negative Child Behaviors. Child Psychiatry & Human Development 2022, 54: 1779-1788. PMID: 35674991, PMCID: PMC9729425, DOI: 10.1007/s10578-022-01377-w.
- Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, Stefanski A. Tirzepatide Once Weekly for the Treatment of Obesity. New England Journal Of Medicine 2022, 387: 205-216. PMID: 35658024, DOI: 10.1056/nejmoa2206038.
- Bautista T, Sinha R, Silverman W, Jastreboff A. 459 Parenting Stress and Drinking to Cope Association with Early Childhood Risk Behaviors. Journal Of Clinical And Translational Science 2022, 6: 91-91. PMCID: PMC9209252, DOI: 10.1017/cts.2022.269.
- Chouairi F, Milner A, Sen S, Guha A, Stewart J, Jastreboff AM, Mori M, Clark KA, Miller PE, Fuery MA, Rogers JG, Notarianni A, Jacoby D, Maulion C, Anwer M, Geirsson A, Desai NR, Ahmad T, Mullan CW. Impact of Obesity on Heart Transplantation Outcomes. Journal Of The American Heart Association 2021, 10: e021346. PMID: 34854316, PMCID: PMC9075353, DOI: 10.1161/jaha.121.021346.
- Gossmann M, Butsch WS, Jastreboff AM. Treating the Chronic Disease of Obesity. Medical Clinics Of North America 2021, 105: 983-1016. PMID: 34688422, DOI: 10.1016/j.mcna.2021.06.005.
- Butsch WS, Hajduk A, Cardel MI, Donahoo WT, Kyle TK, Stanford FC, Zeltser LM, Kotz CM, Jastreboff AM. COVID‐19 vaccines are effective in people with obesity: A position statement from The Obesity Society. Obesity 2021, 29: 1575-1579. PMID: 34212511, PMCID: PMC8441899, DOI: 10.1002/oby.23251.
- Jebeile H, Cardel MI, Kyle TK, Jastreboff AM. Addressing psychosocial health in the treatment and care of adolescents with obesity. Obesity 2021, 29: 1413-1422. PMID: 34431234, DOI: 10.1002/oby.23194.
- Asch RH, Holmes SE, Jastreboff AM, Potenza MN, Baldassarri SR, Carson RE, Pietrzak RH, Esterlis I. Lower synaptic density is associated with psychiatric and cognitive alterations in obesity. Neuropsychopharmacology 2021, 47: 543-552. PMID: 34294874, PMCID: PMC8674236, DOI: 10.1038/s41386-021-01111-5.
- Kidambi S, Batsis JA, Donahoo WT, Jastreboff AM, Kahan S, Saunders KH, Heymsfield SB. Dietary supplements and alternative therapies for obesity: A Perspective from The Obesity Society’s Clinical Committee. Obesity 2021, 29: 1095-1098. PMID: 34159756, DOI: 10.1002/oby.23189.
- BRANCALE J, ATHONVARANGKUL D, SIMONOV M, ALAUSA J, SUBAIR L, HAJDUK A, KANG Y, ARORA T, WILSON F, JASTREBOFF A, LIPSKA K. 1014-P: The Impact of Baseline A1C and Admission Glucose on Mortality among Patients with Diabetes Hospitalized with COVID-19. Diabetes 2021, 70 DOI: 10.2337/db21-1014-p.
- Athonvarangkul D, Gunawan F, Nagel K, Bak L, Herold K, Hwang J, Jastreboff A, Kibbey R, Shulman G, Vatner D, Alausa J, Subair L, Inzucchi S. A Single Virtual Consult Reduces Severe Hyperglycemia in Patients Admitted with COVID19 Infection. Journal Of The Endocrine Society 2021, 5: a335-a335. PMCID: PMC8089507, DOI: 10.1210/jendso/bvab048.683.
- Kang Y, Brancale J, Athonvarangkul D, Alausa J, Subair L, Lipska K, Jastreboff A. Obesity Is Associated With Intensive Care Use and Duration of ICU Stay but Not Mortality Among 3246 Patients Hospitalized With COVID-19. Journal Of The Endocrine Society 2021, 5: a61-a62. PMCID: PMC8089233, DOI: 10.1210/jendso/bvab048.125.
- Clark K, Guha A, Oikonomou E, Jastreboff A, Caraballo C, Weintraub N, Ahmad T, Velazquez E, Miller P, Desai N. WORSE OUTCOMES IN INDIVIDUALS WITH OBESITY UNDERGOING LEFT VENTRICULAR ASSIST DEVICE IMPLANTATION: A LONGITUDINAL INTERMACS STUDY. Journal Of The American College Of Cardiology 2021, 77: 552. DOI: 10.1016/s0735-1097(21)01911-2.
- Bautista T, Fogelman N, Lartigue S, Silverman W, Jastreboff A, Sinha R. 45852 Parenting stress predicts fast food intake in an urban community sample of overweight parents of toddlers. Journal Of Clinical And Translational Science 2021, 5: 35-35. PMCID: PMC8827849, DOI: 10.1017/cts.2021.494.
- Angarita GA, Matuskey D, Pittman B, Costeines JL, Potenza MN, Jastreboff AM, Schmidt HD, Malison RT. Testing the effects of the GLP-1 receptor agonist exenatide on cocaine self-administration and subjective responses in humans with cocaine use disorder. Drug And Alcohol Dependence 2021, 221: 108614. PMID: 33621809, PMCID: PMC8026565, DOI: 10.1016/j.drugalcdep.2021.108614.
- Ackerman C, Spatz E, Lundsberg L, Smith S, Jastreboff A, Reddy U, Illuzzi J, Lipkind H. 724 Association of poor access to care with new diagnosis of chronic hypertension postpartum. American Journal Of Obstetrics And Gynecology 2021, 224: s454. DOI: 10.1016/j.ajog.2020.12.747.
- JOSEPH K, LEVENTHAL J, HWANG S, KNIGHT M, SEO D, LACADIE C, VAN NAME M, CAPRIO S, SHERR J, TAMBORLANE W, SINHA R, JASTREBOFF A. 145-OR: GLP-1 Analogue Effects on Neural Responses to High-Fructose Corn Syrup and Eating Behavior in Obesity. Diabetes 2020, 69 DOI: 10.2337/db20-145-or.
- Bini J, Bhatt S, Hillmer AT, Gallezot JD, Nabulsi N, Pracitto R, Labaree D, Kapinos M, Ropchan J, Matuskey D, Sherwin RS, Jastreboff AM, Carson RE, Cosgrove K, Huang Y. Body Mass Index and Age Effects on Brain 11β-Hydroxysteroid Dehydrogenase Type 1: a Positron Emission Tomography Study. Molecular Imaging And Biology 2020, 22: 1124-1131. PMID: 32133575, PMCID: PMC7351613, DOI: 10.1007/s11307-020-01490-z.
- Monin JK, Sperduto C, Manigault AW, Dutton A, Clark M, Jastreboff A. Mindfulnes-Based Stress Reduction for Older Couples with Metabolic Syndrome: a Pilot Randomized Controlled Trial. Mindfulness 2020, 11: 917-927. PMID: 33343762, PMCID: PMC7748069, DOI: 10.1007/s12671-019-01301-9.
- Mindfulness Based Stress Reduction for Older Couples with Metabolic Syndrome: A Pilot Randomized Controlled TrialMonin JK, Sperduto M, Manigault A, Dutton A, Van Ness P, Ali A, Clark M, Jastreboff AM. Mindfulness Based Stress Reduction for Older Couples with Metabolic Syndrome: A Pilot Randomized Controlled Trial. Mindfulness. Jan 15, 2020.
- Body Mass Index and Age Effects on Brain 11β-Hydroxysteroid Dehydrogenase Type 1: A Positron Emission Tomography StudyBini J , Bhatt S, Hillmer A, Gallezot JD, Nabulsi N, Pracitto R, Labaree D, Kapinos M, Ropchan J, Matuskey D, Sherwin R, Jastreboff AM, Carson RE, Cosgrove K, Huang Y. Journal Molecular Imaging and Biology. Accepted for publication February 20, 2020
- Cardel MI, Jastreboff AM, Kelly AS. Treatment of Adolescent Obesity in 2020. JAMA 2019, 322: 1707-1708. PMID: 31566652, PMCID: PMC7268517, DOI: 10.1001/jama.2019.14725.
- Garvey WT, Jastreboff AM. Commentary from the American Association of Clinical Endocrinologists on the U.S. Preventive Services Task Force Recommandations Regarding Weight Loss Interventions. Endocrine Practice 2019, 25: 394-395. PMID: 31013160, DOI: 10.4158/ep-2018-0597.
- Srivastava G, Fox CK, Kelly AS, Jastreboff AM, Browne AF, Browne NT, Pratt JSA, Bolling C, Michalsky MP, Cook S, Lenders CM, Apovian CM. Clinical Considerations Regarding the Use of Obesity Pharmacotherapy in Adolescents with Obesity. Obesity 2019, 27: 190-204. PMID: 30677262, PMCID: PMC6449849, DOI: 10.1002/oby.22385.
- Jastreboff AM, Kotz CM, Kahan S, Kelly AS, Heymsfield SB. Obesity as a Disease: The Obesity Society 2018 Position Statement. Obesity 2018, 27: 7-9. PMID: 30569641, DOI: 10.1002/oby.22378.
- Jastreboff AM, Chaplin TM, Finnie S, Savoye M, Stults-Kolehmainen M, Silverman WK, Sinha R. Preventing Childhood Obesity Through a Mindfulness-Based Parent Stress Intervention: A Randomized Pilot Study. The Journal Of Pediatrics 2018, 202: 136-142.e1. PMID: 30241766, PMCID: PMC6203652, DOI: 10.1016/j.jpeds.2018.07.011.
- GROSKREUTZ D, SINHA R, LACADIE C, LAM W, HAMZA M, SCHMIDT C, SEO D, HWANG J, BELFORT-DEAGUIAR R, LEVENTHAL J, ROSENBERG S, PARIKH L, CONSTABLE T, SHERWIN R, JASTREBOFF A. Hyperinsulinemia Invokes Greater Brain Perfusion in Reward and Motivation Regions in Obesity. Diabetes 2018, 67 DOI: 10.2337/db18-365-or.
- Sarmiento J, Jastreboff A, Siwakoti K, Rennert N. Abstract #520 Severe Hypercalcemia and Acute Pancreatitis in a Postpartum Woman. Endocrine Practice 2018, 24: 116-117. DOI: 10.1016/s1530-891x(20)47197-6.
- Chao AM, Jastreboff AM, White MA, Grilo CM, Sinha R. Stress, cortisol, and other appetite‐related hormones: Prospective prediction of 6‐month changes in food cravings and weight. Obesity 2017, 25: 713-720. PMID: 28349668, PMCID: PMC5373497, DOI: 10.1002/oby.21790.
- Doyle EA, Quinn SM, Ambrosino JM, Weyman K, Tamborlane WV, Jastreboff AM. Disordered Eating Behaviors in Emerging Adults With Type 1 Diabetes: A Common Problem for Both Men and Women. Journal Of Pediatric Health Care 2016, 31: 327-333. PMID: 27843015, DOI: 10.1016/j.pedhc.2016.10.004.
- Gaiser EC, Gallezot JD, Worhunsky PD, Jastreboff AM, Pittman B, Kantrovitz L, Angarita GA, Cosgrove KP, Potenza MN, Malison RT, Carson RE, Matuskey D. Elevated Dopamine D2/3 Receptor Availability in Obese Individuals: A PET Imaging Study with [11C](+)PHNO. Neuropsychopharmacology 2016, 41: 3042-3050. PMID: 27374277, PMCID: PMC5101552, DOI: 10.1038/npp.2016.115.
- Garvey WT, Mechanick JI, Brett EM, Garber AJ, Hurley DL, Jastreboff AM, Nadolsky K, Pessah-Pollack R, Plodkowski R, Guidelines R. American Association of Clinical Endocrinologists and American College of Endocrinology Comprehensive Clinical Practice Guidelines for Medical Care of Patients with Obesity. Endocrine Practice 2016, 22: 842-884. PMID: 27472012, DOI: 10.4158/ep161356.esgl.
- Quinn SM, Ambrosino JM, Doyle EA, Weyman K, Tamborlane WV, Jastreboff AM. Utility of Psychological Screening of Young Adults with Type 1 Diabetes Transitioning to Adult Providers. Endocrine Practice 2016, 22: 1104-1110. PMID: 27295017, DOI: 10.4158/ep151190.or.
- Garvey WT, Mechanick JI, Brett EM, Garber AJ, Hurley DL, Jastreboff AM, Nadolsky K, Pessah-Pollack R, Plodkowski R, Guidelines R. American Association of Clinical Endocrinologists and American College of Endocrinology Comprehensive Clinical Practice Guidelines Formedical Care of Patients with Obesity. Endocrine Practice 2016, 22: 1-203. PMID: 27219496, DOI: 10.4158/ep161365.gl.
- Jastreboff AM, Sinha R, Arora J, Giannini C, Kubat J, Malik S, Van Name MA, Santoro N, Savoye M, Duran EJ, Pierpont B, Cline G, Constable RT, Sherwin RS, Caprio S. Altered Brain Response to Drinking Glucose and Fructose in Obese Adolescents. Diabetes 2016, 65: 1929-1939. PMID: 27207544, PMCID: PMC5384636, DOI: 10.2337/db15-1216.
- Garrison KA, Sinha R, Lacadie CM, Scheinost D, Jastreboff AM, Constable RT, Potenza MN. Functional Connectivity During Exposure to Favorite-Food, Stress, and Neutral-Relaxing Imagery Differs Between Smokers and Nonsmokers. Nicotine & Tobacco Research 2016, 18: 1820-9. PMID: 26995796, PMCID: PMC4978981, DOI: 10.1093/ntr/ntw088.
- Van Name M, Giannini C, Santoro N, Jastreboff AM, Kubat J, Li F, Kursawe R, Savoye M, Duran E, Dziura J, Sinha R, Sherwin RS, Cline G, Caprio S. Blunted suppression of acyl‐ghrelin in response to fructose ingestion in obese adolescents: The role of insulin resistance. Obesity 2015, 23: 653-661. PMID: 25645909, PMCID: PMC4548801, DOI: 10.1002/oby.21019.
- Hooked on Sugar? Effect of Sucrose on Stress-Induced Cortisol ReleaseJastreboff AM. Hooked on Sugar? Effect of Sucrose on Stress-Induced Cortisol Release. PracticeUpdate website. Available at: http://www.practiceupdate.com/c/24494/48/8. Accessed May 18, 2015.
- Jastreboff AM, Lacadie C, Seo D, Kubat J, Van Name MA, Giannini C, Savoye M, Constable RT, Sherwin RS, Caprio S, Sinha R. Leptin Is Associated With Exaggerated Brain Reward and Emotion Responses to Food Images in Adolescent Obesity. Diabetes Care 2014, 37: 3061-3068. PMID: 25139883, PMCID: PMC4207200, DOI: 10.2337/dc14-0525.
- Jastreboff AM, Sinha R, Lacadie CM, Balodis IM, Sherwin R, Potenza MN. Blunted striatal responses to favorite-food cues in smokers. Drug And Alcohol Dependence 2014, 146: 103-106. PMID: 25444233, PMCID: PMC4272899, DOI: 10.1016/j.drugalcdep.2014.09.006.
- Jastreboff AM, Gaiser EC, Gu P, Sinha R. Sex differences in the association between dietary restraint, insulin resistance and obesity. Eating Behaviors 2014, 15: 286-290. PMID: 24854820, PMCID: PMC4032476, DOI: 10.1016/j.eatbeh.2014.03.008.
- Jastreboff A. Insulin: Food for Thought. Science Translational Medicine 2014, 6 DOI: 10.1126/scitranslmed.3008712.
- Jastreboff A. Giving Leptin a Second Chance. Science Translational Medicine 2014, 6 DOI: 10.1126/scitranslmed.3008433.
- Phentermine/Topiramate and Lifestyle Modification Effective for Weight Loss in DiabeticsJastreboff AM. Phentermine/Topiramate and Lifestyle Modification Effective for Weight Loss in Diabetics. Editorial. PracticeUpdate website. Available at: http://www.practiceupdate.com/journalscan/14806. Accessed December 22, 2014.
- Bariatric Surgery-Induced Weight Loss Causes Remission of Food Addiction in Extreme ObesityJastreboff AM. Bariatric Surgery-Induced Weight Loss Causes Remission of Food Addiction in Extreme Obesity. Editorial. PracticeUpdate website. Available at: http://www.practiceupdate.com/journalscan/11791. Accessed August 19, 2014.
- Insulin: Food for ThoughtJastreboff AM. Insulin: Food for Thought. Science Translational Medicine. Vol. 6, Issue 226, p. 226ec39. March 2014. DOI: 10.1126/scitranslmed.3008712
- Jastreboff A. Diabetes Shrinks the Brain. Science Translational Medicine 2013, 5 DOI: 10.1126/scitranslmed.3008073.
- Jastreboff A. Oxytocin Curbs Cookie Consumption. Science Translational Medicine 2013, 5 DOI: 10.1126/scitranslmed.3007768.
- Jastreboff A. BAT Burns Fat? Cool. Science Translational Medicine 2013, 5 DOI: 10.1126/scitranslmed.3007485.
- Jastreboff A. Linking an Obesity-Associated Gene Variant, Ghrelin, and the Brain. Science Translational Medicine 2013, 5 DOI: 10.1126/scitranslmed.3007044.
- Jastreboff A. The Brains Behind Alcohol Relapse. Science Translational Medicine 2013, 5 DOI: 10.1126/scitranslmed.3006522.
- Jastreboff A. Demystifying the “Magical Cure” for Diabetes. Science Translational Medicine 2013, 5 DOI: 10.1126/scitranslmed.3006449.
- Jastreboff A. Paying Our Sleep Debt in Extra Pounds. Science Translational Medicine 2013, 5 DOI: 10.1126/scitranslmed.3006149.
- Sinha R, Jastreboff AM. Stress as a Common Risk Factor for Obesity and Addiction. Biological Psychiatry 2013, 73: 827-835. PMID: 23541000, PMCID: PMC3658316, DOI: 10.1016/j.biopsych.2013.01.032.
- Hairston KG, Ducharme JL, Treuth MS, Hsueh WC, Jastreboff AM, Ryan KA, Shi X, Mitchell BD, Shuldiner AR, Snitker S. Comparison of BMI and Physical Activity Between Old Order Amish Children and Non-Amish Children. Diabetes Care 2013, 36: 873-878. PMID: 23093661, PMCID: PMC3609522, DOI: 10.2337/dc12-0934.
- Jastreboff AM, Sinha R, Lacadie C, Small DM, Sherwin RS, Potenza MN. Neural Correlates of Stress- and Food Cue–Induced Food Craving in Obesity Association with insulin levels. Diabetes Care 2013, 36: 394-402. PMID: 23069840, PMCID: PMC3554293, DOI: 10.2337/dc12-1112.
- Diabetes Shrinks the BrainJastreboff AM. Diabetes Shrinks the Brain. Science Translational Medicine. Vol. 5, Issue 214, p.214ec199. December 2013. DOI: 10.1126/scitranslmed.3008073
- Oxytocin Curbs Cookie ConsumptionJastreboff AM. Oxytocin Curbs Cookie Consumption. Science Translational Medicine. Vol. 5, Issue 208, p. 208ec173. October 2013. DOI: 10.1126/scitranslamed.3007768
- BAT Burns Fat? CoolJastreboff AM. BAT Burns Fat? Cool. Science Translational Medicine. Vol. 5, Issue 202, p. 202ec148. September 2013. DOI: 10.1126/scitranslmed.3007485
- Linking an Obesity-Associated Gene Variant, Ghrelin, and the BrainJastreboff AM. Linking an Obesity-Associated Gene Variant, Ghrelin, and the Brain. Science Translational Medicine. 2013 July 31; Vol 5, Issue 196, p. 184ec124. DOI: 10.1126/scitranslmed.3007044
- The brains behind alcohol relapseJastreboff AM. The brains behind alcohol relapse. Science Translational Medicine. Vol. 5, Issue 185, p. 185ec82. May 2013. DOI: 10.1126/scitranslmed.300652
- Demystifying the “magical cure” for diabetesJastreboff AM. Demystifying the “magical cure” for diabetes. Science Translational Medicine. Vol. 5, Issue 184, p. 184ec76. May 2013. DOI: 10.1126/scitranslmed.3006449
- Paying our sleep debt in extra poundsJastreboff AM. Paying our sleep debt in extra pounds. Science Translational Medicine.5:178. March 2013. DOI: 10.1126/scitranslmed.3006149
- Sherwin R, Jastreboff AM. Year in Diabetes 2012: The Diabetes Tsunami. The Journal Of Clinical Endocrinology & Metabolism 2012, 97: 4293-4301. PMID: 23185035, PMCID: PMC3513534, DOI: 10.1210/jc.2012-3487.
- Phipps MS, Jastreboff AM, Furie K, Kernan WN. The Diagnosis and Management of Cerebrovascular Disease in Diabetes. Current Diabetes Reports 2012, 12: 314-323. PMID: 22492061, DOI: 10.1007/s11892-012-0271-x.
- Jastreboff AM, Potenza MN, Lacadie C, Hong KA, Sherwin RS, Sinha R. Body Mass Index, Metabolic Factors, and Striatal Activation During Stressful and Neutral-Relaxing States: An fMRI Study. Neuropsychopharmacology 2010, 36: 627-637. PMID: 21048702, PMCID: PMC3055687, DOI: 10.1038/npp.2010.194.
- Jastreboff A, Sherr J. Three Faces of Hypothalamic Tumors. Journal Of Pediatric Endocrinology And Metabolism 2007, 20: 471-472. PMID: 17550209, DOI: 10.1515/jpem.2007.20.4.471.
- Jastreboff AM, Cymet T. Role of the human papilloma virus in the development of cervical intraepithelial neoplasia and malignancy. Postgraduate Medical Journal 2002, 78: 225-8. PMID: 11930025, PMCID: PMC1742321.
Locations
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- Yale Pediatric Endocrinology1 Long Wharf DriveNew Haven, CT 06511
- Yale Diabetes ClinicDana Clinic Building789 Howard Avenue, Ste 2nd FloorNew Haven, CT 06519
- 8 Devine StreetNorth Haven, CT 06473
Biography
Ania M. Jastreboff, MD, PhD, is an adult and pediatric endocrinologist with expertise in obesity medicine and weight management. She cares for patients who have prediabetes, insulin resistance, metabolic syndrome, and type 1 and type 2 diabetes.
Dr. Jastrebroff, who is director of the Yale Obesity Research Center (Y-Weight), says she empathizes with patients who struggle to lose weight or maintain weight loss. “Carrying excess weight and having obesity is not a lifestyle choice. Obesity is a chronic disease and should be treated with the same vigor and integrity as other chronic diseases,” she says. “We are in the infancy of our understanding of the mechanisms that underlie obesity. Many novel treatments are under development, including new anti-obesity medications, endoscopic procedures, and the refining of behavioral and surgical interventions.”
An assistant professor of medicine (endocrinology) and of pediatrics (endocrinology) at Yale School of Medicine, Dr. Jastrebroff says one of her goals is to conduct clinic research that will lead to better treatments for obesity and also have a clear public health impact in mitigating the obesity “pandemic.”
Titles
- Associate Professor of Medicine (Endocrinology)
- Director, Yale Obesity Research Center (Y-Weight)
- Co-Director, Yale Center for Weight Management
Education & Training
- Clinical Research ScholarYale University School of Medicine (2013)
- PhDYale University Graduate School of Arts and Sciences (2011)
- Endocrinology Postdoctoral FellowshipYale University (2011)
- Pediatric Endocrinology Postdoctoral FellowshipYale University (2011)
- Chief ResidentUniversity of Maryland (2006)
- ResidencyUniversity of Maryland School of Medicine (2006)
- MDUniversity of Maryland at Baltimore (2002)
- BABucknell University, Art History (1998)
Additional Information
Honors & Recognitions
- Young Physician-Scientist Award: American Association for Clinical Investigation (ASCI) (2013)
- First Place Poster Award, Yale Multi-Disciplinary Endocrinology & Metabolism Retreat: Yale Univeristy (2013)
- American Diabetes Association Young Investigator Travel Grant Award: American Diabetes Association (ADA) (2013)
- Burroughs Wellcome Fund Travel Award, Translational Science Meeting 2013: Burroughs Wellcome Fund (2013)
- Translational Science Poster Award : Association for Clinical Research Training and Society for Clinical and Translational Science (2013)
- Diabetes Endocrinology Research Center (DRC), Poster Awardee: Yale University (2011)
- Yale Pediatric Fellows’ Research Day, Oral presentation award winner: Yale University (2011)
Board Certifications
- AB of Obesity Medicine, Obesity Medicine (2016)
- AB of Internal Medicine, Endocrinology Diabetes & Metabolism (2012)
Professional Service
- WTNH (Channel 8) (2020): WTNH (Channel 8) On Call: Keto Diet – TV interview on news station: https://www.wtnh.com/news/health/news-8-on-call-keto-diet/
- WTNH (Channel 8) (2020): WTNH (Channel 8). Top 3 dieting trends of 2020. Live TV interview on news station: https://www.wtnh.com/on-air/gmct-at-nine/top-3-dieting-trends-of-2020/
- Better Health (2019): Better Health. 12 diets you should never try, according to health experts. https://www.eatthis.com/unhealthiest-diets-experts/
- Better Health (2019): Better Health. Healthy gifts that are doctor recommended. https://www.eatthis.com/healthy-gifts/
- WTNH (Channel 8) (2019): WTNH (Channel 8) On Call: New policy for children with severe obesity – TV interview on news station: https://www.wtnh.com/lifestyle/health-news/news-8-on-call-new-policy-for-children-with-severe-obesity/
- Huffington Post (2019): Huffington Post. This is your body on Keto. https://www.huffpost.com/entry/keto-effects-body_l_5d9b58abe4b099389803e441
- Health Central (2019): Health Central. When diet and exercise aren’t enough. https://www.healthcentral.com/article/obesity-treatments
- WTNH (Channel 8) (2019): WTNH (Channel 8) Dealing with Diabetes on Campus – Live TV interview on news station: https://www.wtnh.com/on-air/dealing-with-diabetes-on-campus/
- ADA (American Diabetes Association) (2019 - Present): Obesity/Pathogenesis of Obesity Subcommittee
- NIH (2019): NIH Study Section ad hoc reviewer KNOD: Kidney, Nutrition, Obesity, and Diabetes
Publications
- Jastreboff A, Kaplan L, Hartman M. Triple-Hormone-Receptor Agonist Retatrutide for Obesity. Reply. New England Journal Of Medicine 2023, 389: 1629-1630. PMID: 37888927, DOI: 10.1056/nejmc2310645.
- Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trialGrilo C, Lydecker J, Jastreboff A, Pittman B, McKee S. Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial. Obesity 2023, 31: 2762-2773. PMID: 37751990, PMCID: PMC10600891, DOI: 10.1002/oby.23898.
- Kelly A, Arslanian S, Hesse D, Iversen A, Körner A, Schmidt S, Sørrig R, Weghuber D, Jastreboff A. Reducing BMI below the obesity threshold in adolescents treated with once‐weekly subcutaneous semaglutide 2.4 mg. Obesity 2023, 31: 2139-2149. PMID: 37196421, DOI: 10.1002/oby.23808.
- Garvey W, Frias J, Jastreboff A, le Roux C, Sattar N, Aizenberg D, Mao H, Zhang S, Ahmad N, Bunck M, Benabbad I, Zhang X, investigators S, Abalos F, Manghi F, Zaidman C, Vico M, Aizenberg D, Costanzo P, Serra L, MacKinnon I, Hissa M, Vidotti M, Saraiva J, Alves B, Franco D, Moratto O, Murthy S, Goyal G, Yamasaki Y, Sato N, Inoue S, Asakura T, Shestakova M, Khaykina E, Troshina E, Vorokhobina N, Ametov A, Tu S, Yang C, Lee I, Huang C, Ou H, Freeman G, Machineni S, Klein K, Sultan S, Parsa A, Otero-Martinez J, Gonzalez A, Bhargava A, Brian S, Ince C, Plantholt S, Cole J, Lacour A, Vega D, de Souza J, Rohlf J, St. John R, Horowitz B, Audish H, Galindo R, Umpiperrez G, Ard J, Curtis B, Garvey W, Fraser N, Mandry J, Mohseni R, Mayfield R, Powell T, Vance C, Ong S, Lewy-Alterbaum A, Murray A, Al-Karadsheh A, Yacoub T, Roberts K, Fried D, Rosenstock J, Pulla B, Bode B, Frias J, Klaff L, Brazg R, Van J, Tan A, Briskin T, Rhee M, Chaicha-Brom T, Hartley P, Nunez L, Cortes-Maisonet G, Soucie G, Hsia S, Jones T. Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial. The Lancet 2023, 402: 613-626. PMID: 37385275, DOI: 10.1016/s0140-6736(23)01200-x.
- Rosenstock J, Frias J, Jastreboff A, Du Y, Lou J, Gurbuz S, Thomas M, Hartman M, Haupt A, Milicevic Z, Coskun T. Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA. The Lancet 2023, 402: 529-544. PMID: 37385280, DOI: 10.1016/s0140-6736(23)01053-x.
- Jastreboff A, Kaplan L, Frías J, Wu Q, Du Y, Gurbuz S, Coskun T, Haupt A, Milicevic Z, Hartman M. Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial. New England Journal Of Medicine 2023, 389: 514-526. PMID: 37366315, DOI: 10.1056/nejmoa2301972.
- Bautista T, Fogelman N, Lartigue S, Silverman W, Jastreboff A, Sinha R. Association between specific types of parent stressors and fast-food consumption among parents and children. Eating Behaviors 2023, 49: 101724. PMID: 37054487, PMCID: PMC10247538, DOI: 10.1016/j.eatbeh.2023.101724.
- Weghuber D, Khandpur N, Boyland E, Mazur A, Frelut M, Forslund A, Vlachopapadopoulou E, Erhardt É, Vania A, Molnar D, Ring‐Dimitriou S, Caroli M, Mooney V, Forhan M, Ramos‐Salas X, Pulungan A, Holms J, O'Malley G, Baker J, Jastreboff A, Baur L, Thivel D. Championing the use of people‐first language in childhood overweight and obesity to address weight bias and stigma: A joint statement from the European‐Childhood‐Obesity‐Group (ECOG), the European‐Coalition‐for‐People‐Living‐with‐Obesity (ECPO), the International‐Paediatric‐Association (IPA), Obesity‐Canada, the European‐Association‐for‐the‐Study‐of‐Obesity Childhood‐Obesity‐Task‐Force (EASO‐COTF), Obesity Action Coalition (OAC), The Obesity Society (TOS) and the World‐Obesity‐Federation (WOF). Pediatric Obesity 2023, 18: e13024. PMID: 37002830, DOI: 10.1111/ijpo.13024.
- Aronne L, Jastreboff A, Le Roux C, Malik R, Ahmad N, Liu B, Bunck M, Zhang S, Stefanski A, Lautenbach A. Tirzepatide reduces body weight across body mass index (BMI) categories: A SURMOUNT-1 pre-specified analysis. Diabetologie Und Stoffwechsel 2023, 18: s42-s43. DOI: 10.1055/s-0043-1767938.
- New Frontiers in Obesity Treatment: GLP-1 and Nascent Nutrient-Stimulated Hormone-Based TherapeuticsJastreboff A, Kushner R. New Frontiers in Obesity Treatment: GLP-1 and Nascent Nutrient-Stimulated Hormone-Based Therapeutics. Annual Review Of Medicine 2023, 74: 125-139. PMID: 36706749, DOI: 10.1146/annurev-med-043021-014919.
- Aronne L, Bramblette S, Ingelfinger J, Jastreboff A, Machineni S, Massie N, Rosen C. When Weight Impacts Health. New England Journal Of Medicine 2023, 388: e2. PMID: 36630621, DOI: 10.1056/nejmp2215794.
- Kahn S, Anderson C, Buse J, Selvin E, Angell S, Aroda V, Castle J, Cheng A, Danne T, Echouffo-Tcheugui J, Florez J, Gadgil M, Gastaldelli A, Green J, Jastreboff A, Kanaya A, Kandula N, Kovesdy C, Laiteerapong N, Nadeau K, Pop-Busui R, Powe C, Rebholz C, Rickels M, Sattar N, Shaw J, Sims E, Utzschneider K, Vella A, Zhang C. "The Times They Are A-Changin'" at Diabetes Care. Diabetes Care 2022, 46: 3-5. PMID: 36548704, DOI: 10.2337/dci22-0045.
- Aronne L, Bramblette S, Huett-Garcia A, Ingelfinger J, Jastreboff A, Machineni S, Massie N, Rosen C. Weight and Health — Pathophysiology and Therapies. New England Journal Of Medicine 2022, 387: e62. PMID: 36516089, DOI: 10.1056/nejmp2214423.
- Chouairi F, Mullan C, Ahmed A, Bhinder J, Guha A, Miller P, Jastreboff A, Fuery M, Chiravuri M, Geirsson A, Desai N, Maulion C, Sen S, Ahmad T, Anwer M. Clinical implications of Type 2 diabetes on outcomes after cardiac transplantation. PLOS ONE 2022, 17: e0273111. PMID: 36516178, PMCID: PMC9750001, DOI: 10.1371/journal.pone.0273111.
- Bini J, Gallezot J, Li S, Lim K, Emery P, Kapinos M, Ropchan J, Nabulsi N, Jastreboff A, Huang Y, Carson R. RF12 | PSUN106 Quantifying Liver and Brain Levels of 11β-hydroxysteroid Dehydrogenase Type 1 in Obesity Using Positron Emission Tomography Imaging. Journal Of The Endocrine Society 2022, 6: a29-a30. PMCID: PMC9624872, DOI: 10.1210/jendso/bvac150.062.
- Friedman AN, Schauer PR, Beddhu S, Kramer H, le Roux C, Purnell JQ, Sunwold D, Tuttle KR, Jastreboff AM, Kaplan LM. Obstacles and opportunities in managing coexisting obesity and CKD: Report of a scientific workshop cosponsored by the National Kidney Foundation and The Obesity Society. Obesity 2022, 30: 2340-2350. PMID: 36268562, DOI: 10.1002/oby.23599.
- Friedman AN, Schauer PR, Beddhu S, Kramer H, le Roux CW, Purnell JQ, Sunwold D, Tuttle KR, Jastreboff AM, Kaplan LM. Obstacles and Opportunities in Managing Coexisting Obesity and CKD: Report of a Scientific Workshop Cosponsored by the National Kidney Foundation and The Obesity Society. American Journal Of Kidney Diseases 2022, 80: 783-793. PMID: 36280397, DOI: 10.1053/j.ajkd.2022.06.007.
- Jastreboff AM, Aronne LJ, Stefanski A. Tirzepatide Once Weekly for the Treatment of Obesity. Reply. New England Journal Of Medicine 2022, 387: 1434-1435. PMID: 36239655, DOI: 10.1056/nejmc2211120.
- Bini J, Parikh L, Lacadie C, Hwang JJ, Shah S, Rosenberg SB, Seo D, Lam K, Hamza M, De Aguiar RB, Constable T, Sherwin RS, Sinha R, Jastreboff AM. Stress-level glucocorticoids increase fasting hunger and decrease cerebral blood flow in regions regulating eating. NeuroImage Clinical 2022, 36: 103202. PMID: 36126514, PMCID: PMC9486604, DOI: 10.1016/j.nicl.2022.103202.
- Fogelman N, Schwartz J, Chaplin TM, Jastreboff AM, Silverman WK, Sinha R. Parent Stress and Trauma, Autonomic Responses, and Negative Child Behaviors. Child Psychiatry & Human Development 2022, 54: 1779-1788. PMID: 35674991, PMCID: PMC9729425, DOI: 10.1007/s10578-022-01377-w.
- Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, Stefanski A. Tirzepatide Once Weekly for the Treatment of Obesity. New England Journal Of Medicine 2022, 387: 205-216. PMID: 35658024, DOI: 10.1056/nejmoa2206038.
- Bautista T, Sinha R, Silverman W, Jastreboff A. 459 Parenting Stress and Drinking to Cope Association with Early Childhood Risk Behaviors. Journal Of Clinical And Translational Science 2022, 6: 91-91. PMCID: PMC9209252, DOI: 10.1017/cts.2022.269.
- Chouairi F, Milner A, Sen S, Guha A, Stewart J, Jastreboff AM, Mori M, Clark KA, Miller PE, Fuery MA, Rogers JG, Notarianni A, Jacoby D, Maulion C, Anwer M, Geirsson A, Desai NR, Ahmad T, Mullan CW. Impact of Obesity on Heart Transplantation Outcomes. Journal Of The American Heart Association 2021, 10: e021346. PMID: 34854316, PMCID: PMC9075353, DOI: 10.1161/jaha.121.021346.
- Gossmann M, Butsch WS, Jastreboff AM. Treating the Chronic Disease of Obesity. Medical Clinics Of North America 2021, 105: 983-1016. PMID: 34688422, DOI: 10.1016/j.mcna.2021.06.005.
- Butsch WS, Hajduk A, Cardel MI, Donahoo WT, Kyle TK, Stanford FC, Zeltser LM, Kotz CM, Jastreboff AM. COVID‐19 vaccines are effective in people with obesity: A position statement from The Obesity Society. Obesity 2021, 29: 1575-1579. PMID: 34212511, PMCID: PMC8441899, DOI: 10.1002/oby.23251.
- Jebeile H, Cardel MI, Kyle TK, Jastreboff AM. Addressing psychosocial health in the treatment and care of adolescents with obesity. Obesity 2021, 29: 1413-1422. PMID: 34431234, DOI: 10.1002/oby.23194.
- Asch RH, Holmes SE, Jastreboff AM, Potenza MN, Baldassarri SR, Carson RE, Pietrzak RH, Esterlis I. Lower synaptic density is associated with psychiatric and cognitive alterations in obesity. Neuropsychopharmacology 2021, 47: 543-552. PMID: 34294874, PMCID: PMC8674236, DOI: 10.1038/s41386-021-01111-5.
- Kidambi S, Batsis JA, Donahoo WT, Jastreboff AM, Kahan S, Saunders KH, Heymsfield SB. Dietary supplements and alternative therapies for obesity: A Perspective from The Obesity Society’s Clinical Committee. Obesity 2021, 29: 1095-1098. PMID: 34159756, DOI: 10.1002/oby.23189.
- BRANCALE J, ATHONVARANGKUL D, SIMONOV M, ALAUSA J, SUBAIR L, HAJDUK A, KANG Y, ARORA T, WILSON F, JASTREBOFF A, LIPSKA K. 1014-P: The Impact of Baseline A1C and Admission Glucose on Mortality among Patients with Diabetes Hospitalized with COVID-19. Diabetes 2021, 70 DOI: 10.2337/db21-1014-p.
- Athonvarangkul D, Gunawan F, Nagel K, Bak L, Herold K, Hwang J, Jastreboff A, Kibbey R, Shulman G, Vatner D, Alausa J, Subair L, Inzucchi S. A Single Virtual Consult Reduces Severe Hyperglycemia in Patients Admitted with COVID19 Infection. Journal Of The Endocrine Society 2021, 5: a335-a335. PMCID: PMC8089507, DOI: 10.1210/jendso/bvab048.683.
- Kang Y, Brancale J, Athonvarangkul D, Alausa J, Subair L, Lipska K, Jastreboff A. Obesity Is Associated With Intensive Care Use and Duration of ICU Stay but Not Mortality Among 3246 Patients Hospitalized With COVID-19. Journal Of The Endocrine Society 2021, 5: a61-a62. PMCID: PMC8089233, DOI: 10.1210/jendso/bvab048.125.
- Clark K, Guha A, Oikonomou E, Jastreboff A, Caraballo C, Weintraub N, Ahmad T, Velazquez E, Miller P, Desai N. WORSE OUTCOMES IN INDIVIDUALS WITH OBESITY UNDERGOING LEFT VENTRICULAR ASSIST DEVICE IMPLANTATION: A LONGITUDINAL INTERMACS STUDY. Journal Of The American College Of Cardiology 2021, 77: 552. DOI: 10.1016/s0735-1097(21)01911-2.
- Bautista T, Fogelman N, Lartigue S, Silverman W, Jastreboff A, Sinha R. 45852 Parenting stress predicts fast food intake in an urban community sample of overweight parents of toddlers. Journal Of Clinical And Translational Science 2021, 5: 35-35. PMCID: PMC8827849, DOI: 10.1017/cts.2021.494.
- Angarita GA, Matuskey D, Pittman B, Costeines JL, Potenza MN, Jastreboff AM, Schmidt HD, Malison RT. Testing the effects of the GLP-1 receptor agonist exenatide on cocaine self-administration and subjective responses in humans with cocaine use disorder. Drug And Alcohol Dependence 2021, 221: 108614. PMID: 33621809, PMCID: PMC8026565, DOI: 10.1016/j.drugalcdep.2021.108614.
- Ackerman C, Spatz E, Lundsberg L, Smith S, Jastreboff A, Reddy U, Illuzzi J, Lipkind H. 724 Association of poor access to care with new diagnosis of chronic hypertension postpartum. American Journal Of Obstetrics And Gynecology 2021, 224: s454. DOI: 10.1016/j.ajog.2020.12.747.
- JOSEPH K, LEVENTHAL J, HWANG S, KNIGHT M, SEO D, LACADIE C, VAN NAME M, CAPRIO S, SHERR J, TAMBORLANE W, SINHA R, JASTREBOFF A. 145-OR: GLP-1 Analogue Effects on Neural Responses to High-Fructose Corn Syrup and Eating Behavior in Obesity. Diabetes 2020, 69 DOI: 10.2337/db20-145-or.
- Bini J, Bhatt S, Hillmer AT, Gallezot JD, Nabulsi N, Pracitto R, Labaree D, Kapinos M, Ropchan J, Matuskey D, Sherwin RS, Jastreboff AM, Carson RE, Cosgrove K, Huang Y. Body Mass Index and Age Effects on Brain 11β-Hydroxysteroid Dehydrogenase Type 1: a Positron Emission Tomography Study. Molecular Imaging And Biology 2020, 22: 1124-1131. PMID: 32133575, PMCID: PMC7351613, DOI: 10.1007/s11307-020-01490-z.
- Monin JK, Sperduto C, Manigault AW, Dutton A, Clark M, Jastreboff A. Mindfulnes-Based Stress Reduction for Older Couples with Metabolic Syndrome: a Pilot Randomized Controlled Trial. Mindfulness 2020, 11: 917-927. PMID: 33343762, PMCID: PMC7748069, DOI: 10.1007/s12671-019-01301-9.
- Mindfulness Based Stress Reduction for Older Couples with Metabolic Syndrome: A Pilot Randomized Controlled TrialMonin JK, Sperduto M, Manigault A, Dutton A, Van Ness P, Ali A, Clark M, Jastreboff AM. Mindfulness Based Stress Reduction for Older Couples with Metabolic Syndrome: A Pilot Randomized Controlled Trial. Mindfulness. Jan 15, 2020.
- Body Mass Index and Age Effects on Brain 11β-Hydroxysteroid Dehydrogenase Type 1: A Positron Emission Tomography StudyBini J , Bhatt S, Hillmer A, Gallezot JD, Nabulsi N, Pracitto R, Labaree D, Kapinos M, Ropchan J, Matuskey D, Sherwin R, Jastreboff AM, Carson RE, Cosgrove K, Huang Y. Journal Molecular Imaging and Biology. Accepted for publication February 20, 2020
- Cardel MI, Jastreboff AM, Kelly AS. Treatment of Adolescent Obesity in 2020. JAMA 2019, 322: 1707-1708. PMID: 31566652, PMCID: PMC7268517, DOI: 10.1001/jama.2019.14725.
- Garvey WT, Jastreboff AM. Commentary from the American Association of Clinical Endocrinologists on the U.S. Preventive Services Task Force Recommandations Regarding Weight Loss Interventions. Endocrine Practice 2019, 25: 394-395. PMID: 31013160, DOI: 10.4158/ep-2018-0597.
- Srivastava G, Fox CK, Kelly AS, Jastreboff AM, Browne AF, Browne NT, Pratt JSA, Bolling C, Michalsky MP, Cook S, Lenders CM, Apovian CM. Clinical Considerations Regarding the Use of Obesity Pharmacotherapy in Adolescents with Obesity. Obesity 2019, 27: 190-204. PMID: 30677262, PMCID: PMC6449849, DOI: 10.1002/oby.22385.
- Jastreboff AM, Kotz CM, Kahan S, Kelly AS, Heymsfield SB. Obesity as a Disease: The Obesity Society 2018 Position Statement. Obesity 2018, 27: 7-9. PMID: 30569641, DOI: 10.1002/oby.22378.
- Jastreboff AM, Chaplin TM, Finnie S, Savoye M, Stults-Kolehmainen M, Silverman WK, Sinha R. Preventing Childhood Obesity Through a Mindfulness-Based Parent Stress Intervention: A Randomized Pilot Study. The Journal Of Pediatrics 2018, 202: 136-142.e1. PMID: 30241766, PMCID: PMC6203652, DOI: 10.1016/j.jpeds.2018.07.011.
- GROSKREUTZ D, SINHA R, LACADIE C, LAM W, HAMZA M, SCHMIDT C, SEO D, HWANG J, BELFORT-DEAGUIAR R, LEVENTHAL J, ROSENBERG S, PARIKH L, CONSTABLE T, SHERWIN R, JASTREBOFF A. Hyperinsulinemia Invokes Greater Brain Perfusion in Reward and Motivation Regions in Obesity. Diabetes 2018, 67 DOI: 10.2337/db18-365-or.
- Sarmiento J, Jastreboff A, Siwakoti K, Rennert N. Abstract #520 Severe Hypercalcemia and Acute Pancreatitis in a Postpartum Woman. Endocrine Practice 2018, 24: 116-117. DOI: 10.1016/s1530-891x(20)47197-6.
- Chao AM, Jastreboff AM, White MA, Grilo CM, Sinha R. Stress, cortisol, and other appetite‐related hormones: Prospective prediction of 6‐month changes in food cravings and weight. Obesity 2017, 25: 713-720. PMID: 28349668, PMCID: PMC5373497, DOI: 10.1002/oby.21790.
- Doyle EA, Quinn SM, Ambrosino JM, Weyman K, Tamborlane WV, Jastreboff AM. Disordered Eating Behaviors in Emerging Adults With Type 1 Diabetes: A Common Problem for Both Men and Women. Journal Of Pediatric Health Care 2016, 31: 327-333. PMID: 27843015, DOI: 10.1016/j.pedhc.2016.10.004.
- Gaiser EC, Gallezot JD, Worhunsky PD, Jastreboff AM, Pittman B, Kantrovitz L, Angarita GA, Cosgrove KP, Potenza MN, Malison RT, Carson RE, Matuskey D. Elevated Dopamine D2/3 Receptor Availability in Obese Individuals: A PET Imaging Study with [11C](+)PHNO. Neuropsychopharmacology 2016, 41: 3042-3050. PMID: 27374277, PMCID: PMC5101552, DOI: 10.1038/npp.2016.115.
- Garvey WT, Mechanick JI, Brett EM, Garber AJ, Hurley DL, Jastreboff AM, Nadolsky K, Pessah-Pollack R, Plodkowski R, Guidelines R. American Association of Clinical Endocrinologists and American College of Endocrinology Comprehensive Clinical Practice Guidelines for Medical Care of Patients with Obesity. Endocrine Practice 2016, 22: 842-884. PMID: 27472012, DOI: 10.4158/ep161356.esgl.
- Quinn SM, Ambrosino JM, Doyle EA, Weyman K, Tamborlane WV, Jastreboff AM. Utility of Psychological Screening of Young Adults with Type 1 Diabetes Transitioning to Adult Providers. Endocrine Practice 2016, 22: 1104-1110. PMID: 27295017, DOI: 10.4158/ep151190.or.
- Garvey WT, Mechanick JI, Brett EM, Garber AJ, Hurley DL, Jastreboff AM, Nadolsky K, Pessah-Pollack R, Plodkowski R, Guidelines R. American Association of Clinical Endocrinologists and American College of Endocrinology Comprehensive Clinical Practice Guidelines Formedical Care of Patients with Obesity. Endocrine Practice 2016, 22: 1-203. PMID: 27219496, DOI: 10.4158/ep161365.gl.
- Jastreboff AM, Sinha R, Arora J, Giannini C, Kubat J, Malik S, Van Name MA, Santoro N, Savoye M, Duran EJ, Pierpont B, Cline G, Constable RT, Sherwin RS, Caprio S. Altered Brain Response to Drinking Glucose and Fructose in Obese Adolescents. Diabetes 2016, 65: 1929-1939. PMID: 27207544, PMCID: PMC5384636, DOI: 10.2337/db15-1216.
- Garrison KA, Sinha R, Lacadie CM, Scheinost D, Jastreboff AM, Constable RT, Potenza MN. Functional Connectivity During Exposure to Favorite-Food, Stress, and Neutral-Relaxing Imagery Differs Between Smokers and Nonsmokers. Nicotine & Tobacco Research 2016, 18: 1820-9. PMID: 26995796, PMCID: PMC4978981, DOI: 10.1093/ntr/ntw088.
- Van Name M, Giannini C, Santoro N, Jastreboff AM, Kubat J, Li F, Kursawe R, Savoye M, Duran E, Dziura J, Sinha R, Sherwin RS, Cline G, Caprio S. Blunted suppression of acyl‐ghrelin in response to fructose ingestion in obese adolescents: The role of insulin resistance. Obesity 2015, 23: 653-661. PMID: 25645909, PMCID: PMC4548801, DOI: 10.1002/oby.21019.
- Hooked on Sugar? Effect of Sucrose on Stress-Induced Cortisol ReleaseJastreboff AM. Hooked on Sugar? Effect of Sucrose on Stress-Induced Cortisol Release. PracticeUpdate website. Available at: http://www.practiceupdate.com/c/24494/48/8. Accessed May 18, 2015.
- Jastreboff AM, Lacadie C, Seo D, Kubat J, Van Name MA, Giannini C, Savoye M, Constable RT, Sherwin RS, Caprio S, Sinha R. Leptin Is Associated With Exaggerated Brain Reward and Emotion Responses to Food Images in Adolescent Obesity. Diabetes Care 2014, 37: 3061-3068. PMID: 25139883, PMCID: PMC4207200, DOI: 10.2337/dc14-0525.
- Jastreboff AM, Sinha R, Lacadie CM, Balodis IM, Sherwin R, Potenza MN. Blunted striatal responses to favorite-food cues in smokers. Drug And Alcohol Dependence 2014, 146: 103-106. PMID: 25444233, PMCID: PMC4272899, DOI: 10.1016/j.drugalcdep.2014.09.006.
- Jastreboff AM, Gaiser EC, Gu P, Sinha R. Sex differences in the association between dietary restraint, insulin resistance and obesity. Eating Behaviors 2014, 15: 286-290. PMID: 24854820, PMCID: PMC4032476, DOI: 10.1016/j.eatbeh.2014.03.008.
- Jastreboff A. Insulin: Food for Thought. Science Translational Medicine 2014, 6 DOI: 10.1126/scitranslmed.3008712.
- Jastreboff A. Giving Leptin a Second Chance. Science Translational Medicine 2014, 6 DOI: 10.1126/scitranslmed.3008433.
- Phentermine/Topiramate and Lifestyle Modification Effective for Weight Loss in DiabeticsJastreboff AM. Phentermine/Topiramate and Lifestyle Modification Effective for Weight Loss in Diabetics. Editorial. PracticeUpdate website. Available at: http://www.practiceupdate.com/journalscan/14806. Accessed December 22, 2014.
- Bariatric Surgery-Induced Weight Loss Causes Remission of Food Addiction in Extreme ObesityJastreboff AM. Bariatric Surgery-Induced Weight Loss Causes Remission of Food Addiction in Extreme Obesity. Editorial. PracticeUpdate website. Available at: http://www.practiceupdate.com/journalscan/11791. Accessed August 19, 2014.
- Insulin: Food for ThoughtJastreboff AM. Insulin: Food for Thought. Science Translational Medicine. Vol. 6, Issue 226, p. 226ec39. March 2014. DOI: 10.1126/scitranslmed.3008712
- Jastreboff A. Diabetes Shrinks the Brain. Science Translational Medicine 2013, 5 DOI: 10.1126/scitranslmed.3008073.
- Jastreboff A. Oxytocin Curbs Cookie Consumption. Science Translational Medicine 2013, 5 DOI: 10.1126/scitranslmed.3007768.
- Jastreboff A. BAT Burns Fat? Cool. Science Translational Medicine 2013, 5 DOI: 10.1126/scitranslmed.3007485.
- Jastreboff A. Linking an Obesity-Associated Gene Variant, Ghrelin, and the Brain. Science Translational Medicine 2013, 5 DOI: 10.1126/scitranslmed.3007044.
- Jastreboff A. The Brains Behind Alcohol Relapse. Science Translational Medicine 2013, 5 DOI: 10.1126/scitranslmed.3006522.
- Jastreboff A. Demystifying the “Magical Cure” for Diabetes. Science Translational Medicine 2013, 5 DOI: 10.1126/scitranslmed.3006449.
- Jastreboff A. Paying Our Sleep Debt in Extra Pounds. Science Translational Medicine 2013, 5 DOI: 10.1126/scitranslmed.3006149.
- Sinha R, Jastreboff AM. Stress as a Common Risk Factor for Obesity and Addiction. Biological Psychiatry 2013, 73: 827-835. PMID: 23541000, PMCID: PMC3658316, DOI: 10.1016/j.biopsych.2013.01.032.
- Hairston KG, Ducharme JL, Treuth MS, Hsueh WC, Jastreboff AM, Ryan KA, Shi X, Mitchell BD, Shuldiner AR, Snitker S. Comparison of BMI and Physical Activity Between Old Order Amish Children and Non-Amish Children. Diabetes Care 2013, 36: 873-878. PMID: 23093661, PMCID: PMC3609522, DOI: 10.2337/dc12-0934.
- Jastreboff AM, Sinha R, Lacadie C, Small DM, Sherwin RS, Potenza MN. Neural Correlates of Stress- and Food Cue–Induced Food Craving in Obesity Association with insulin levels. Diabetes Care 2013, 36: 394-402. PMID: 23069840, PMCID: PMC3554293, DOI: 10.2337/dc12-1112.
- Diabetes Shrinks the BrainJastreboff AM. Diabetes Shrinks the Brain. Science Translational Medicine. Vol. 5, Issue 214, p.214ec199. December 2013. DOI: 10.1126/scitranslmed.3008073
- Oxytocin Curbs Cookie ConsumptionJastreboff AM. Oxytocin Curbs Cookie Consumption. Science Translational Medicine. Vol. 5, Issue 208, p. 208ec173. October 2013. DOI: 10.1126/scitranslamed.3007768
- BAT Burns Fat? CoolJastreboff AM. BAT Burns Fat? Cool. Science Translational Medicine. Vol. 5, Issue 202, p. 202ec148. September 2013. DOI: 10.1126/scitranslmed.3007485
- Linking an Obesity-Associated Gene Variant, Ghrelin, and the BrainJastreboff AM. Linking an Obesity-Associated Gene Variant, Ghrelin, and the Brain. Science Translational Medicine. 2013 July 31; Vol 5, Issue 196, p. 184ec124. DOI: 10.1126/scitranslmed.3007044
- The brains behind alcohol relapseJastreboff AM. The brains behind alcohol relapse. Science Translational Medicine. Vol. 5, Issue 185, p. 185ec82. May 2013. DOI: 10.1126/scitranslmed.300652
- Demystifying the “magical cure” for diabetesJastreboff AM. Demystifying the “magical cure” for diabetes. Science Translational Medicine. Vol. 5, Issue 184, p. 184ec76. May 2013. DOI: 10.1126/scitranslmed.3006449
- Paying our sleep debt in extra poundsJastreboff AM. Paying our sleep debt in extra pounds. Science Translational Medicine.5:178. March 2013. DOI: 10.1126/scitranslmed.3006149
- Sherwin R, Jastreboff AM. Year in Diabetes 2012: The Diabetes Tsunami. The Journal Of Clinical Endocrinology & Metabolism 2012, 97: 4293-4301. PMID: 23185035, PMCID: PMC3513534, DOI: 10.1210/jc.2012-3487.
- Phipps MS, Jastreboff AM, Furie K, Kernan WN. The Diagnosis and Management of Cerebrovascular Disease in Diabetes. Current Diabetes Reports 2012, 12: 314-323. PMID: 22492061, DOI: 10.1007/s11892-012-0271-x.
- Jastreboff AM, Potenza MN, Lacadie C, Hong KA, Sherwin RS, Sinha R. Body Mass Index, Metabolic Factors, and Striatal Activation During Stressful and Neutral-Relaxing States: An fMRI Study. Neuropsychopharmacology 2010, 36: 627-637. PMID: 21048702, PMCID: PMC3055687, DOI: 10.1038/npp.2010.194.
- Jastreboff A, Sherr J. Three Faces of Hypothalamic Tumors. Journal Of Pediatric Endocrinology And Metabolism 2007, 20: 471-472. PMID: 17550209, DOI: 10.1515/jpem.2007.20.4.471.
- Jastreboff AM, Cymet T. Role of the human papilloma virus in the development of cervical intraepithelial neoplasia and malignancy. Postgraduate Medical Journal 2002, 78: 225-8. PMID: 11930025, PMCID: PMC1742321.
Locations
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- Yale Pediatric Endocrinology1 Long Wharf DriveNew Haven, CT 06511
- Yale Diabetes ClinicDana Clinic Building789 Howard Avenue, Ste 2nd FloorNew Haven, CT 06519
- 8 Devine StreetNorth Haven, CT 06473
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1 of 3
- Yale Pediatric Endocrinology1 Long Wharf DriveNew Haven, CT 06511
- Yale Diabetes ClinicDana Clinic Building789 Howard Avenue, Ste 2nd FloorNew Haven, CT 06519
- 8 Devine StreetNorth Haven, CT 06473